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If you can match your opponent card-for-card with generally stronger spells, eventually you are likely to come out ahead

Hold on to Prince Eric, Seafaring Prince to keep her safe, and plenty of the healing cards like Healing Glow and Julieta Madrigal, Excellent Cook , and you should be able to keep Isabela in play long enough to get you the win

Compared with Teysa Karlov, Lavinia, Azorius Renegade, Judith, the Scourge Diva and Nikya of the Old Ways, Zegana is pretty disappointing, but I still think she has some utility and having 3 abilities rather than 2 somewhat makes up for her lack of raw power

Red has upped the game and I expect a period of urgent readjustment in the typically meandering pace of cube evolution