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Functional heterogeneity: The SSP exerts opposing functions in tumor cells versus tumor-associated cells, such as M2-type macrophages and CD8 + T cells
In conclusion, the present study demonstrated for the first time that the GPX4 gene could be involved in the development of CS in patients with EH
(2017) designed and characterized FOXO4-DRI and demonstrated its selective activity against senescent cells in culture and in naturally aged mice
p53-pS15 combined with FOXO4 in the nucleus of senescent cells inhibits p53 into the cytoplasm to mediate apoptosis and halt the cell cycle 9,11
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