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RNA-seq For MEFs 13 The concentration of total RNA extractions was quantified with the Nanodrop One (Thermo Fisher), and RNA integrity was assessed with the Bioanalyzer 2100 RNA Nano assay (Agilent)

We used a hypergeometric test against GO gene-set collections to analyse the function of the top 25% of genes whose CT was induced by OSKM expression, and whose CT could be reduced with vitamin B 12 (Extended Data Fig

Key Features MOTS-C 5-Amino-1MQ AOD-9604 Bundle Contents Specifications Storage Conditions Research Use Only Disclaimer Additional Information Each batch undergoes internal analytical verification using chromatographic and spectrometric methods prior to lyophilisation

Since IV infusions often combine B12 with complementary nutrients, the broader formulation can occasionally introduce sensitivities that a standalone B12 shot would not