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J Clin Oncol 10(7):11711175 Miller AA, De Silva TM, Jackman KA, Sobey CG (2007) Effect of gender and sex hormones on vascular oxidative stress

Mitochondrial dysfunction in HD includes impaired electron transport chain activity, reduced mitochondrial biogenesis, and defective mitophagy, all of which contribute to increased oxidative stress and neuronal damage [165]

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Therefore, HSPs are not only involved in maintaining cellular homeostasis under stress but also serve as key molecular links between heat stress and the pathogenesis of male infertility