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Name: can semaglutide cause stomach ulcers tirzepatide Why Constipation Matters While on GLP-1/GIP-1 Medications Constipation Ozempic & the Gut: What
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9,10 GLP-1 is secreted in response to nutrient intake, particularly glucose and fatty acids, in the intestinal lumen

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By analogy with semaglutide (where the STEP-4 withdrawal trial demonstrated substantial weight regain within 12 months of discontinuation), researchers should anticipate that weight regain is likely following cessation of any GLP-1 class compound, including retatrutide

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