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The combination of reduced intake and impaired absorption creates a trajectory toward deficiency over months and years of treatment
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A clinical study on modified growth hormone releasing factor (CJC-1295) demonstrated sustained increases in GH and IGF-1 levels following repeated dosing with a favorable safety profile, supporting the use of consistent dosing over multi-week protocols
Eisenberg T, Knauer H, Schauer A, Bttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Frhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F (2009) Induction of autophagy by spermidine promotes longevity
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