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Another study showed that elevated insulin levels promote the proliferation of thecal cells and increase the secretion of androgens, including luteinizing hormone (LH), while also upregulating the expression of cytochrome P450 and insulin growth factor-1 (IGF-1) receptors (107)

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For patients continuing semaglutide, a 24-hour clear-liquid diet before surgery may be recommended as a risk mitigation strategy for those with higher risk profiles, rather than extended solid-food fasting