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Monitor appetite, side effects, and weight over the first four weeks
It is reasonable to speculate that MASH resolution could lead to regression of liver fibrosis, a significant factor in major adverse liver outcomes (MALO) such as ascites, hepatic encephalopathy, variceal bleeding, liver transplantation or liver-related mortality
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Those meeting three or more ATP III criteria (elevated triglycerides, low HDL, elevated fasting glucose, hypertension, central obesity) experience approximately 40% greater lipid improvement than patients without metabolic syndrome, based on STEP-2 subgroup analyses 3
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