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CMAJ 2009
The theory is that long-term use of semaglutide, particularly without a controlled diet, could lead to vitamin B12 deficiency due to the effects on gastric emptying
Functions as a for metabolic reaction required for synthesis of purines and pyrimidines: co-enzyme The reaction depends on methyl cobalamin as a co-factor and is also dependent on folate, in which the methyl group of methyltetrahydrofolate is transferred to homocysteine to form methionine and tetrahydrofolate
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