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[16] [17] Weight reduction can normalize some of these abnormalities, potentially improving metabolic outcomes through cortisol-independent mechanisms
The first step in the pre-operative care of a patient on GLP-1RAs should involve an assessment of the risk of aspiration, taking into account factors that may increase this risk, including the escalation phase of GLP-1RA dosing or a high-dose protocol, the presence of gastrointestinal symptoms of delayed gastric emptying (e.g
Alternative approaches to oral cysteamine therapy have been proposed for cystinosis [82, 146, 151, 152]
GLP-1 medications reduce appetite, but rapid or aggressive calorie deficits increase the risk of muscle loss
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