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In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)
Its not just anecdotal, either: One randomized experiment from researchers at Rice University found that people reported feeling more negative emotions when hearing that somebody lost weight using a GLP-1 drug compared to losing weight with diet or exercise, or not even losing weight at all
According to FDA guidance, compounded medications are not FDA-approved as finished products
Regardless of the results proven by clinical studies and the fact that youve been following all the instructions, your experience with semaglutide may not be as significant as you expected
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