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It was subsequently approved for use in individuals with a BMI of 30 or higher or those with a BMI of 27 or higher who also have at least one weight-related health problem to promote weight loss

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Niacin - Pregnancy and Breastfeeding Warnings

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Wu, J., Cao, M., Hu, M., Gong, Y., Xue, J., Yang, Y., & Zhou, H

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In contrast, lignans such as schisandrin, schisandrin A and schisandrin B are not P-gp substrates, which enhances their potential for intracellular accumulation and targeted therapeutic effects, contributing to their increased efficacy

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