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Interestingly, semaglutide robustly activates PSN and PVT neurons, possibly by tanycyte-mediated uptake [51], suggesting a convergence of endogenous GLP-1 and GLP-1R agonist action in the neural pathways that suppress food intake in the PVT
Whether you are on compounded semaglutide or a brand-name formulation, the physiological response follows similar patterns
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