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Some doctors argue that ketosis may increase the risk of kidney stones, high cholesterol, impaired immune function, eye disease, osteoporosis, and protein deficiency

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Nicassio L, Fracasso F, Sirago G, Musicco C, Picca A, Marzetti E, Calvani R, Cantatore P, Gadaleta MN, Pesce V (2017) Dietary supplementation with acetyl-l-carnitine counteracts age-related alterations of mitochondrial biogenesis, dynamics and antioxidant defenses in brain of old rats

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The GlyNAC combination (glycine + NAC) showed multi-system improvements in a 16-week RCT in older adults, including corrected glutathione deficiency, reduced oxidative stress, improved mitochondrial function, and enhanced physical performance

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