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In this study, mice were injected into the ears with either 750,000 or 25,000 human A375 melanoma cells, followed by a 2-day treatment, starting 24 h later, with either saline (control group), ES2 peptide, dabrafenib (a senescence inducer), or a combination of ES2 and dabrafenib [128]
Products with 1-2% GHK-Cu concentration in stable formulations with appropriate pH and penetration enhancers create stronger improvements more likely persisting after treatment, while lower concentrations (0.1-0.5%) or degraded products may produce subtle temporary effects disappearing quickly upon discontinuation
The lack of regulation in these markets raises concerns about the authenticity and purity of the peptide
For research purposes, experts advise starting with a conservative dose of 0.5mg/daily and increasing as needed: Daily Sermorelin Dose: Start at 0.5mg via subcutaneous injections and titrate to up to 2mg/daily, depending on the subjects response
