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62 Two double-blind RCTs investigated the effectiveness of B12 in adults who had been suffering from low back pain for more than 6 months, and both found significantly better pain reduction in the B12 compared with the placebo group
Excess vitamin B12 is linked to increased cancer growth in certain types of cancer.[ref] Methotrexate, a chemotherapy drug, works by inhibiting the production of methyl folate, thus limiting methionine and DNA synthesis for cell growth
Older patients or those with multiple comorbidities may experience slower improvement
Research indicates that AOD-9604 may act, at least in part, through beta-3 adrenergic receptor (3-AR) signaling a pathway tightly associated with fat oxidation in visceral and brown adipose tissue
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