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Moreover, cytosolic mitochondrial DNA elevation induced by reduced NRF2 signaling in PERK-deficient MDSCs led to STING-dependent production of anti-tumor Type-I Interferon

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Our data also suggest that liver might be the major site responsible for the glucose-lowering effect and insulinotropic action of T3

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Despite the contradictory data regarding kidney outcomes, two surrogate outcomes benefit the most from combined therapy: the decline in eGFR slope and the reduction in urinary albumin-to-creatinine ratio

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