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[01:43-02:14] resveratrol is an anti-aging supplement it's really popular back to like 20 years ago it also can increase the GLP medications effects interestingly our patients that have osteoarthritis a lot of them are on GLP not a lot but a good chunk of them are on GLP medications they're trying to lose weight which helps their arthritis right so many of them take curcumin Curcumin, we've talked about before in our board-approved nutritional courses for physical therapists and some of our other videos

Animal studies showed increased risks of pregnancy loss, fetal abnormalities, and growth issues at doses similar to human therapeutic levels

Monitor for new or worsening depression and mood changes

Any switch should always be done under clinical supervision