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Libraries were prepared by collapsing and purifying PCR products using the Thermo Fisher PureLink PCR Purification Kit (Thermo Fisher, K310001), according to the manufacturers protocol
Propensity score matching Within each BMI subgroup, cohorts were matched 1:1 using nearest-neighbor propensity score matching without replacement
The composite clinical endpoint and CRP levels, a biomarker of inflammation, were also significantly improved
however, this is not guaranteed
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