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Our skin faces oxidative stressan imbalance between free radicals and our bodys defensesfrom daily exposure to: UV Radiation: Sun exposure (remember to wear SPF 24/7) Environmental Pollutants: Smog, ozone, and particulate matter Lifestyle factors such as poor diet, stress, and lack of sleep
Consequently, the oxidized nicotinamide adenine dinucleotide/ATP ratio is depleted, and glyceraldehyde-3-phosphate dehydrogenase is inactivated, leading to the activation of harmful pathways such as the polyol, hexosamine and protein kinase C (PKC) pathways, as well as the subsequent accumulation of advanced glycation end products, resulting in microvascular damage
However, the duration of the course depends on your bodys reaction to vitamin B12 shots
no combined effect is claimed or implied, and combining the compounds in one vial does not produce any outcome
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