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It should be noted that dose-proportionality was assessed using only two dose levels (1 and 2 mg/kg), and the observed linearity in systemic exposure should be interpreted within this dose range
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Genomic DNA was released by using SDS Lysis Buffer, and sonicated to 200-1000 bps
High expression of PD-L1 is a distinguishing feature of cancer cells, and high-intensity PD-L1 signaling induces reduced glycolysis, glutamine degradation and free FA metabolism in effector T cells
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