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Maintenance and discontinuation SURMOUNT-4, continue vs placebo switch after lead-in to about 20.9% loss: stopping regained about +14% over 52 weeks while continuing lost a further -5.5%
no completed large-scale human efficacy trials for muscle, recovery or anti-aging
Research indicates that short peptides of this class may exhibit affinity for DNA or chromatin-associated proteins, suggesting a possible role in epigenetic modulation
Individual factors like age, weight, and baseline IGF-1 guide dose adjustments
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