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Plasma MOTS-c concentrations were similar in lean and obese individuals, whereas plasma MOTS-c concentrations were negatively correlated with insulin sensitivity, an effect that was better reflected in lean individuals
This finding not only provides a novel mechanistic framework for unifying research on cancers and pituitary adenoma but also expands the therapeutic landscape by positioning USP8 as a common target with relevance across diverse pathological contexts
Lu Z, et al
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