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Note: If you choose to take it at night, ensure you have finished your last meal at least two to three hours prior

It doesn't mean don't use them

Its derived from a naturally occurring protein found in human stomach (gastric) juice, which is part of the reason researchers first became interested in it the body already produces a version of this compound as part of its natural protective processes

R NAT2 polymorphisms alter catalytic activity primarily through effects on protein stability and degradation rates rather than changes to the active site itself (slow acetylator alleles produce unstable protein that is rapidly ubiquitinated and degraded)